Sanofi BioGENEius Challenge Canada (SBCC), Celebrating 20 years

Southwestern Ontario Projects 2013

by sbccadmin on February 20, 2013

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1. Name: Naima Raiza
School: Northern Collegiate Institute, Sarnia
Title: Investigating the Variables that Affect the Celliobiase Degradation of Cellulose
Description: In this project, the two most abundant organic compounds on Earth, cellulose and hemicellulose, will be degraded by bacteria using cellulose-rich cotton and hemicellulose-rich wheat straw sources. The speed and efficiency of breakdown for cotton and wheat straw will be compared in order to determine whether cellulose or hemicellulose is a more successful energy source. The success of cellulose and hemicellulose can be applied for a groundwater purification study.

2. Name: Jesse MacAlpine
School: Huron Park Secondary School, Woodstock
Title: Allyl isothiocyanate as an apicomlexan plastid-targetting anti-malarial drug therapy for Plasmodium falicaparum
Description: Malaria is a disease afflicting approximately 300 million people worldwide. The parasite that causes malaria, the plasmodium, has been suggested to have evolved from a plant-like species, resulting in the possibility of a herbicide being used to treat this disease. One compound with established use in developing countries, mustard oil, has been shown to inhibit the growth of plants. This experiment found that mustard oil was an effective anti-malarial drug, reducing parasite growth significantly over a wide range of concentrations. With application of mustard oil, the life stage of the plasmodium is shortened and the parasite cannot survive to replicate in cells and continue to spread throughout the body. As an inexpensive oil, this compound has potential in replacing the existing anti-malarial drugs of which have gained resistance in recent years.

3. Name: Alex Vasile
School: Centennial Collegiate and Vocational Institute, Guelph
Title: Heat Shock Protein 70’s Role in the Protection

4. Name: Junyi (Sarah) Wu
School: Assumption College School, Brantford
Title: Salivary Rapid Diagnostic Test for Plasmodium Falciparum via Aptasensor and Colorimetric Detection Technology

5. Name: Alex Inglis
School: Centennial Collegiate Vocational Institute
Title: A Physiological Based Pharmacokinetic Model of Toluene Concentration in Various Bodily and Cerebral Regions
Description: Toluene, a popular commercial solvent, is used in the production of many household products, such as adhesives, paint thinners, and moisturizing creams. Because of its accessibility and relatively easy application, it is a popular psychoactive drug among adolescents in low-income communities and homes. The short term effects of the drug, while being well documented, are not well understood. The objective of this project is to provide researchers with a model capable of predicting concentrations of Toluene in the human body, in order to better understand and predict the effects that exposure will have.

6. Name: Varsha Jayasankar
School: Sir Winston Churchill Secondary School, St. Catherines
Title: CACE II: Identifying Novel Anti-Microbial Compounds in Mango Ginger

7. Name: Dragos Chiriac
School: Vincent Massey Secondary School, Windsor
Title: Hydrogen Sulfide Assaying by Measuring the Resistance of Nafion
Description: To determine a method for actively measuring the amount of hydrogen sulfide produced by micro organism. Nafion, a synthetic membrane, is covered with silver chloride. As the micro organisms release hydrogen sulfide it will react with the silver in the nafion membrane to create silver sulfide. Silver sulfide is conductive and by measuring the change in electrical current we can plot the correlation between the amount of silver sulfide and the resistance provided by the nafion strip.We hope that we are able to extrapolate from the graph to easily determine the amount of hydrogen sulfide produced by these microorganisms.

8. Names: Nina Falek and Cristina Matei
School: Centennial Collegiate and Vocational Institute, Guelph
Title: Effects of Resveratol and Rosiglitazone on Enzymes Involved in Fat Metabolism in Adipose Tissue

9. Names: Melaine Grodin and Shawn Liu
School: Vincent Massey Secondary School, Windsor
Title: Expanding Bone Marrow Stem Cells for Transplantation

10. Names: Tina Tang and Anisa Morava
School: Centennial Collegiate and Vocational Institute,Guelph
Title: The Use of Fluorescent Proteins as a Non-Toxic Sunscreen Component

11. Name: Jeongho Jang
School: A.B. Lucas Secondary School, London
Title: Gene Therapy for Epilepsy

12. Names: Jason Ly and Priyinka Dhillion
School: Sir John A. Macdonald, Hamiltion
Title: Do Hygienic Measures Affect your Likelihood of Getting Ill from the Common Bacteria on Public Surfaces

13. Name: Linda Lu
School: Waterloo Collegiate Institute, Waterloo
Title: Antioxidants Can be Very Bad

14. Name: Janelle Tam
School: Waterloo Collegiate Institute, Waterloo
Title: Development Of Nanocrystalline Cellulose As a Novel Antimicrobial

15. Name: Victor Puvanendran
School: A.B. Lucas Secondary School
Title: Intake and Viability of Transfected Human Cardiac Myocytes (SLC8A3) in Presence of Anthracycline

16. Names: Yazan Obeidi and Mackenzie Billings
School: Centennial Collegiate and Vocational Institute, Guelph
Title: Preventing Spoilage using Bacteriophage

17. Names: Annie Cheng and Simone Smith
School: Centennial Collegiate and Vocational Institute, Guelph
Title: Transfection of Saccharomyces cerevisiae with Cellulsome Plasmid.

18. Names: Daisy An and Lia Huo
School: Vincent Massey Secondary School, Windsor
Title: Determining Systemical Methods to Combat Acne Using Existent Treatments
Description: Our goal is to study the cures that can be found for acne on the human skin and then catalog these cures through testing them on bacteria obtained from acne plagued skin. We will be growing bacterial cultures ourselves, comparing bacteria found on healthy skin to those from skin
with acne and looking at the bacteria that cause this skin disease. We hope to further our knowledge on acne and on curing it in a well-directed way.

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